SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1; ATP-dependent helicase 1; hHEL1 (SMARCAD1, KIAA1122)

Function

• probable ATP-dependent DNA helicase
• phosphorylated upon DNA damage, probably by ATM or ATR

Structure

• belongs to the SNF2/RAD54 helicase family
• contains 2 CUE domains
• contains 1 helicase ATP-binding domain
• contains 1 helicase C-terminal domain

Compartment

nucleus (putative)

Alternative splicing

named isoforms=2

Expression

ubiquitous

More general terms

• SWI/SNF-related matrix-associated actin dependent regulator of chromatin subfamily A
• helicase (DNA unwinding protein, DNA untwisting protein)
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=56916
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:56916
• UniProt: http://www.uniprot.org/uniprot/Q9H4L7.html