inwardly-rectifying K+ channel J3; G protein-activated inward rectifier K+ channel 1; GIRK1; K+ channel, inwardly rectifying subfamily J member 3; inward rectifier K+ channel Kir3.1 (KCNJ3, GIRK1)

Function

• inwardly-rectifying K+ channel controlled by G proteins
• role in regulating the heartbeat
• associates with GIRK2, GIRK3 or GIRK4 to form a G-protein activated heteromultimer pore-forming unit; the resulting inward current is much larger (putative)

Structure

• belongs to the inward rectifier-type K+ channel family

Compartment

membrane

More general terms

• inwardly-rectifying K+ channel subfamily J
• phosphoprotein
• protein subunit

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=3760
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:3760
• OMIM: https://mirror.omim.org/entry/601534
• UniProt: http://www.uniprot.org/uniprot/P48549.html