glucosidase 2 subunit beta; glucosidase II subunit beta; protein kinase C substrate 60.1 kD protein heavy chain; PKCSH; 80K-H protein (PRKCSH, G19P1)

Function

• regulatory subunit of glucosidase 2
• glycan metabolism; N-glycan metabolism
• binds glycosylated PTPRC (putative)

Structure

• heterodimer of a catalytic alpha subunit (GANAB) & a beta subunit (PRKCSH)
• contains 2 EF-hand domains
• contains 1 PRKCSH domain

Compartment

endoplasmic reticulum (putative)

Pathology

• defects in PRKCSH are a cause of polycystic liver disease

More general terms

• phosphoprotein
• enzyme regulatory subunit

Component of

• glucosidase 2

Database

• UniProt: http://www.uniprot.org/uniprot/P14314.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=5589
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5589
• OMIM: https://mirror.omim.org/entry/174050
• OMIM: https://mirror.omim.org/entry/177060