Ras-related protein Rab-1A; YPT1-related protein (RAB1A RAB1)
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Function
- probably required for transit of protein from the ER through Golgi compartment
- binds GTP & GDP
- intrinsic GTPase activity
- phosphorylated by CDC2 kinase during mitosis
- may interact with YIPF5 (putative)
Structure
belongs to the small GTPase superfamily, Rab family
Compartment
Alternative splicing
named isoforms=3
More general terms
References
- ↑ Kahn RA, Der CJ, Bokoch GM. The ras superfamily of GTP-binding proteins: guidelines on nomenclature. FASEB J. 1992 May;6(8):2512-3. PMID: https://www.ncbi.nlm.nih.gov/pubmed/1592203
- ↑ Bourne HR et al, The GTPase superfamily: a conserved switch for diverse cell functions Nature 348:125 1990 PMID: https://www.ncbi.nlm.nih.gov/pubmed/2122258
- ↑ Seabra MC et al Rab GTPases, intracellular traffic and disease Trends in Molecular Medicine 8:23, 2002 PMID: https://www.ncbi.nlm.nih.gov/pubmed/11796263
- ↑ Entrez Gene http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=5861
- ↑ UniProt http://www.uniprot.org/uniprot/P62820.html