eukaryotic initiation factor 3 subunit 7 (eukaryotic translation initiation factor 3 subunit D, eIF-3 zeta, eiF3 p66, eIF3d, EIF3S7)

Function

• binds to the 40S ribosome & promotes the binding of methionyl-tRNAi & mRNA
• associates with the subunit p170 of eIF-3
• phosphorylated upon DNA damage, probably by ATM or ATR

Structure

belongs to the eIF-3 subunit D family

More general terms

• eukaryotic initiation factor subunit
• phosphoprotein

Component of

• eukaryotic initiation factor 3; ribosome dissociation factor (eIF3)

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:8664
• OMIM: https://mirror.omim.org/entry/603915
• UniProt: http://www.uniprot.org/uniprot/O15371.html