dynactin (subunit 2 dynactin 50 KD subunit, dynamitin, dynactin p50, 50 kD dynein-associated polypeptide, DCTN-50, DCTN2, DCTN50)

Function

• subunit of dynactin
• modulates cytoplasmic dynein binding to an organelle,
• role in prometaphase chromosome alignment & spindle organization during mitosis
• role in synapse formation during brain development (putative)
• interacts with BICD2 (putative)
• interacts with MAPRE1

Structure

belongs to the dynactin subunit 2 family

Compartment

cytoplasm, cytoskeleton, peripheral membrane

More general terms

• protein subunit
• phosphoprotein

Component of

• dynactin

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1054
• OMIM: https://mirror.omim.org/entry/607376
• UniProt: http://www.uniprot.org/uniprot/Q13561.html