APAF1-interacting protein (APIP)

Function

• anti-apoptotic function
• prevents muscleischemic damage
• inhibits the cytochrome c-dependent & APAF1-mediated cell death
• interacts with APAF1

Cofactor: binds 1 Zn+2 per subunit

Compartment

cytoplasm

Alternative splicing

named isoforms=2

Expression

• ubiquitously expressed
• high expression in skeletal muscle, heart, kidney

More general terms

• metalloprotein

Database

• UniProt: http://www.uniprot.org/uniprot/Q96GX9.html