prickle-like protein 1 (REST/NRSF-interacting LIM domain protein 1, PRICKLE1, RILP)

Function

• interacts with REST, necessary for nuclear localization of REST
• nuclear receptor (putative)

Structure

• prenylated on Cys-828
• contains 3 LIM zinc-binding domains
• contains 1 PET domain

Compartment

• nucleus, nuclear membrane
• a smaller amount is detected in the cytosol

Expression

• expressed in placenta > brain, lung, liver, kidney, pancreas

More general terms

• prenyl protein

Database

• OMIM: https://mirror.omim.org/entry/608500
• UniProt: http://www.uniprot.org/uniprot/Q96MT3.html