pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32 (DEAH box protein 32, DEAD/H helicase-like protein 1, DHLP1, DEAD/H box 32, HuDDX32)

Structure

• belongs to the DEAD box helicase family, DEAH subfamily
• contains 1 helicase ATP-binding domain
• contains 1 helicase C-terminal domain

Compartment

• nucleus, mitochondrion

Alternative splicing

named isoforms=2

Expression

• expressed in lymphoid tissues (at protein level)
• expressed in brain, heart, skeletal muscle, colon, thymus, spleen, kidney, liver, small intestine, placenta, lung, lymphoid tissues & blood leukocytes
• up-regulated by ionomycin in T lymphocytes

Pathology

• down-regulated in acute lymphoblastic leukemia

More general terms

• DEAH box ATP-dependent helicase
• mitochondrial protein
• splicing factor; snRNP-associated protein

Database

• OMIM: https://mirror.omim.org/entry/607960
• UniProt: http://www.uniprot.org/uniprot/Q7L7V1.html