tRNA-nucleotidyltransferase 1, mitochondrial (mitochondrial tRNA nucleotidyl transferase CCA-adding, mt tRNA adenylyltransferase, mt tRNA CCA-pyrophosphorylase, mt tRNA CCA-diphosphorylase, mt CCA-adding enzyme, TRNT1)

Function

• adds & repairs conserved 3'-CCA sequence necessary for attachment of amino acids to the 3' terminus of tRNA
• uses CTP & ATP as substrates
• monomer, homodimer, disulfide-linked

Cofactor: Mg+2

Structure

• monomer, homodimer, disulfide-linked
• belongs to tRNA nucleotidyltransferase/poly(A) polymerase family

Compartment

mitochondrion

Alternative splicing

named isoforms=3

More general terms

• nucleotidyltransferase
• mitochondrial protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q96Q11.html