glyoxalase domain-containing protein 4 (GLOD4, C17orf25, CGI-150, My027)

Function

interacts with NUDT9

Structure

belongs to the glyoxalase 1 family

Compartment

mitochondria (probable)

Alternative splicing

named isoforms=3

Expression

• expressed in heart, brain, liver, kidney, pancreas & placenta
• not expressed in skeletal muscle & lung

Pathology

• expression is decreased in hepatocellular carcinoma compared to adjacent non-cancerous liver tissue
• transfection in hepatocellular carcinoma cells & overexpression can inhibit the cell growth

More general terms

• mitochondrial protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q9HC38.html