lipoyltransferase 1, mitochondrial; lipoate biosynthesis protein; lipoate-protein ligase; lipoyl ligase (LIPT1)

Function

• lipoate biosynthesis
• catalyzes transfer of the lipoyl group from lipoyl-AMP to Lys of the lipoate-dependent enzymes

Structure

belongs to the lplA family

Compartment

mitochondrion

Expression

• expressed in skeletal muscle, heart > kidney, pancreas > liver, brain, placenta, lung

More general terms

• transferase
• ligase or synthetase
• mitochondrial protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=51601
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:51601
• OMIM: https://mirror.omim.org/entry/610284
• UniProt: http://www.uniprot.org/uniprot/Q9Y234.html