3-mercaptopyruvate sulfurtransferase (MST, MPST TST2)

Function

• transfer of a sulfur ion to cyanide or sulfur compound
• weak rhodanese activity
• role in cyanide degradation or in thiosulfate biosynthesis

3-mercaptopyruvate + cyanide  <-->  pyruvate +  thiocyanate

Structure

• monomer or disulfide-linked homodimer
• contains 2 rhodanese domains

Compartment

cytoplasm Originally thought to be rhodanese

More general terms

• sulfurtransferase
• mitochondrial protein

Database

• UniProt: http://www.uniprot.org/uniprot/P25325.html
• OMIM: https://mirror.omim.org/entry/602496