thiosulfate sulfurtransferase; rhodanese (TST)

Function

• formation of iron-sulfur complexes
• cyanide detoxification
• modification of sulfur-containing enzymes
• thiol compounds can act as sulfur ion acceptors
• weak mercaptopyruvate sulfurtransferase (MST) activity

Thiosulfate + cyanide   <-->  sulfite + thiocyanate

Structure

• contains 2 rhodanese domains

Compartment

• mitochondrial matrix

More general terms

• sulfurtransferase
• mitochondrial protein

Database

• OMIM: https://mirror.omim.org/entry/180370
• UniProt: http://www.uniprot.org/uniprot/Q16762.html