nontreponemal serologic test for syphilis

Principle

• nontreponemal serologic tests used in the diagnosis of syphilis include:
  • VDRL reagin slide
  • rapid plasma reagin circle card (RPR)
  • unheated serum reagin (USR)
  • toluidine red unheated serum test (TRUST)
• all of these tests are based upon detection of immunoglobulin, IgG or IgM (reagin) directed against non treponemal antigens
• all nontreponemal assays utilize an active phospholipid (cardiolipin) antigen combined with lecithin & cholesterol in a colloidal particle

More general terms

• serologic test for syphilis

More specific terms

• rapid plasma reagin (RPR)
• toluidine red unheated serum test (TRUST)
• unheated serum reagin (USR)
• VDRL reagin slide (VDRL)

Component of

• obstetric panel HIV
• obstetric panel