reagin

Introduction

• Wolf Eisner's term for antibody.
• Old term for the Wassermann antibody which is evoked during syphilitic infections & combines with cardiolipin in the presence of lecithin & cholesterol (IgM). It is distinct from the treponema-immobilizing antibody.
• Antibodies that mediate immune hypersensitivity reactions (IgE in humans).

More general terms

• serology

More specific terms

• rapid plasma reagin (RPR)
• reagin Ab in CSF
• unheated serum reagin (USR)
• VDRL reagin slide (VDRL)

Additional terms

• cardiolipin
• cholesterol
• phosphatidylcholine (lecithin)
• serologic test for syphilis