carbonic anhydrase-5B (carbonic anhydrase VB, mitochondrial carbonic anhydrase)
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Function
- reversible hydration of CO2
H2CO3 <--> CO2 + H2O
Cofactor: Zn+2 (putative)
Structure
belongs to the alpha-carbonic anhydrase family
Compartment
Expression
- strongest expression in heart, pancreas, kidney, placenta, lung, & skeletal muscle
- not expressed in liver
Notes
- inhibition of mitochondrial carbonic anhydrase suggested to have benefit for aging & neurodegenerative disease[2]
More general terms
References
- ↑ UniProt http://www.uniprot.org/uniprot/Q9Y2D0.html
- ↑ Jump up to: 2.0 2.1 University of Nottingham. Oct 10, 2016 Cell protein offers new hope in fighting the effects of aging. https://www.nottingham.ac.uk/news/pressreleases/2016/october/cell-protein-offers-new-hope-in-fighting-the-effects-of-aging.aspx