centrosomal protein of 63 kD (CEP63)

Function

• required for normal spindle assembly
• role in DNA damage response
  • following DNA double strand breaks (DSBs), it is delocalized from centrosomes, leading to inactivate spindle assembly & delay mitotic progression (putative)

Structure

belongs to the CEP63 family

Compartment

• cytoplasm, cytoskeleton, centrosome

Alternative splicing

named isoforms=4

More general terms

• centrosomal protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=80254
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:80254
• UniProt: http://www.uniprot.org/uniprot/Q96MT8.html