ataxin-3-like protein (Machado-Joseph disease protein 1-like, ATXN3L, MJDL)

Function

• may bind to histones & regulate transcription
• may act as a deubiquitinating enzyme

Structure

• contains 1 Josephin domain
• contains 2 UIM repeats (ubiquitin-interacting motif repeats)

Compartment

nucleus

Notes

• may be product of a pseudogene, absence of intron in gene

More general terms

• nuclear protein
• ataxin
• hydrolase

Additional terms

• ataxin-3; Machado-Joseph disease protein 1; spinocerebellar ataxia type 3 protein (ATXN3, ATX3, MJD, MJD1, SCA3)
• spinocerebellar ataxia type 3 (SCA-3); Machado-Joseph disease; Azorean disease

Database

• UniProt: http://www.uniprot.org/uniprot/Q9H3M9.html