Transmembrane protein 176B (protein LR8, TMEM176B, LR8)

Function

• role in process of maturation of dendritic cells
• required for development of cerebellar granule cells

Structure

belongs to the TMEM176 family

Compartment

• nuclear envelope

Expression

• expressed in lung & dermal fibroblasts
• down-regulated in activated dendritic cells Pathoology: up-regulated in fibrotic lung

More general terms

• transmembrane 4 protein
• nuclear protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q3YBM2.html