pre-mRNA-processing factor 6 (PRP6 homolog, U5 snRNP-associated 102 kD protein, U5-102 kD protein, PRPF6, C20orf14)

Function

• role pre-mRNA splicing
• may act in the tri-snRNP complex as a bridging factor between U5 & U4/U6 snRNPs in the late step of spliceosome assembly
• may be necessary for tri-snRNP formation
• associates with U5 snRNP particle
• associates with U4/U6 snRNP particle
• identified in the spliceosome C complex

Structure

contains 9 HAT repeats

Compartment

nucleus

More general terms

• nuclear protein

Component of

• spliceosome C complex

Database

• UniProt: http://www.uniprot.org/uniprot/O94906.html