ankyrin repeat domain-containing protein 23 (diabetes-related ankyrin repeat protein, muscle ankyrin repeat protein 3, ANKRD23, DARP)

Function

• role in energy metabolism (putative)
• molecular link between myofibrillar stretch-induced signaling pathways & muscle gene expression (putative)
• interacts with titin/TTN & MYPN

Structure

contains 4 ANK repeats

Compartment

• nucleus
• sarcomeric I-band & some intercalated disks

Alternative splicing

named isoforms=2

Expression

• expressed in heart, skeletal muscle & brown adipose tissues

More general terms

• ankyrin repeat domain protein (ANKRD)
• nuclear protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q86SG2.html