unconventional prefoldin RPB5 interactor; protein NNX3; RNA polymerase II subunit 5-mediating protein; RPB5-mediating protein (RMP, URI1, C19orf2. NNX3 .URI)

Function

• seems to be a scaffolding protein able to assemble a prefoldin-like complex that contains PFDs & proteins with roles in transcription & ubiquitination
• component of the URI complex that contains PFDN2, POLR2E/RPB5, RUVBL2, RUVBL1 & RMP. interacts with POLR2E/RPB5

Structure

• belongs to the RNA polymerase II subunit 5-mediating protein family

Compartment

nucleus

Alternative splicing

named isoforms=2

Expression

ubiquitous

More general terms

• nuclear protein
• phosphoprotein

Additional terms

• RNA polymerases 1, 2, & 3 subunit RPABC1 (RNA polymerases 1, 2, & 3 subunit ABC1, RNA polymerase 2 23 kD subunit, RNA polymerase 2 subunit E, RNA polymerase 2 subunit 5, POLR2E, RPABC1, RPB25, RBP5, XAP4)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=8725
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:8725
• OMIM: https://mirror.omim.org/entry/603494
• UniProt: http://www.uniprot.org/uniprot/O94763.html