RNA polymerases 1, 2, & 3 subunit RPABC1 (RNA polymerases 1, 2, & 3 subunit ABC1, RNA polymerase 2 23 kD subunit, RNA polymerase 2 subunit E, RNA polymerase 2 subunit 5, POLR2E, RPABC1, RPB25, RBP5, XAP4)

Function

• common component of RNA polymerases 1, 2 & 3
• in RNA polymerase 2, POLR2E is part of the lower jaw surrounding the central large cleft & thought to grab the incoming DNA template, seems to be the major component in this process (putative)
• subunit is present in 2-fold molar excess over other subunits
• interacts with RMP
• interacts with HBV protein

Structure

• N-terminus is blocked
• belongs to the archaeal rpoH/eukaryotic RPB5 RNA polymerase subunit family

Compartment

nucleus (putative)

More general terms

• rna polymerase subunit
• nuclear protein

Additional terms

• unconventional prefoldin RPB5 interactor; protein NNX3; RNA polymerase II subunit 5-mediating protein; RPB5-mediating protein (RMP, URI1, C19orf2. NNX3 .URI)

Component of

• RNA polymerase 1
• RNA polymerase-2
• RNA polymerase 3

Database

• UniProt: http://www.uniprot.org/uniprot/P19388.html
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5434
• OMIM: https://mirror.omim.org/entry/180664