sal-like protein 4; zinc finger protein SALL4 (SALL4)

Function

• probable transcription factor
• interacts with NANOG (putative)

Structure

• belongs to the sal C2H2-type Zn+2-finger protein family
• contains 7 C2H2-type Zn+2 fingers

Compartment

nucleus (probable)

Expression

expressed in testis

Pathology

• defects in SALL4 are the cause of
  • Duane-radial ray syndrome
  • IVIC syndrome

More general terms

• nuclear protein
• C2H2 type zinc finger protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=57167
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:57167
• OMIM: https://mirror.omim.org/entry/147750
• OMIM: https://mirror.omim.org/entry/607323
• OMIM: https://mirror.omim.org/entry/607343
• UniProt: http://www.uniprot.org/uniprot/Q9UJQ4.html