Fanconi anemia group B protein; protein FACB; Fanconi anemia-associated polypeptide of 95 kDa; FAAP95 (FANCB)

Function

• DNA repair protein required for FANCD2 ubiquitination
• component of multisubunit FA complex

Compartment

nucleus

Pathology

• defects in FANCB are the cause of cause of
  • Fanconi anemia complementation group B
  • X-linked VACTERL-H

More general terms

• nuclear protein
• protein subunit
• phosphoprotein

Additional terms

• Fanconi anemia
• Fanconi anemia complementation group B

Component of

• Fanconi anemia complementation group complex (FA complex)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=2187
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2187
• OMIM: https://mirror.omim.org/entry/227650
• OMIM: https://mirror.omim.org/entry/300514
• OMIM: https://mirror.omim.org/entry/300515
• OMIM: https://mirror.omim.org/entry/314390
• UniProt: http://www.uniprot.org/uniprot/Q8NB91.html