TBP-associated factor 172; TAF-172; TAF(II)170; BTAF1 RNA polymerase 2; B-TF2D transcription factor-associated 170-kd; BTAF1; TATA box-binding protein-associated factor RNA polymerase 2 170-kd (TAF172)

Function

• regulates transcription in association with TATA binding protein (TBP)
• removes TBP from the TATA box in an ATP-dependent manner
• associates with TBP to form B-TFIID. binds DRAP1

Structure

• belongs to the SNF2/RAD54 helicase family
• contains 8 HEAT repeats
• contains 1 helicase ATP-binding domain
• contains 1 helicase C-terminal domain

Compartment

nucleus

More general terms

• nuclear protein
• HEAT repeat-containing protein (HEATR)
• phosphoprotein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:9044
• OMIM: https://mirror.omim.org/entry/605191
• UniProt: http://www.uniprot.org/uniprot/O14981.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=9044