dual specificity protein phosphatase 21; low molecular weight dual specificity phosphatase 21; LMW-DSP21 (DUSP21, LMWDSP21)

Function

• can dephosphorylate single & diphosphorylated synthetic MAPK peptides, with preference for the phospho-Tyr & diphosphorylated forms over phospho-Thr

Structure

• belongs to the protein-tyrosine phosphatase family non-receptor class dual specificity subfamily
• contains 1 tyrosine-protein phosphatase domain

Compartment

• cytoplasm, nucleus, mitochondrial inner membrane
• peripheral membrane, matrix side

Expression

expressed in testis

More general terms

• dual specificity phosphatase
• nuclear protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=63904
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:63904
• OMIM: https://mirror.omim.org/entry/300678
• UniProt: http://www.uniprot.org/uniprot/Q9H596.html