Ran-specific GTPase-activating protein; Ran-binding protein 1; RanBP1 (RANBP1)

Function

• inhibits GTP exchange on Ran
• forms a Ran-GTP-RANBP1 trimeric complex
• increases GTP hydrolysis induced by GTPase activating protein RANGAP1
• may play a role in control progression through the cell cycle by regulating transport of protein & nucleic acids across the nuclear membrane

Structure

• belongs to the RANBP1 family
• contains 1 RanBD1 domain

More general terms

• nuclear protein
• phosphoprotein

Database

• UniProt: http://www.uniprot.org/uniprot/P43487.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=5902
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5902
• OMIM: https://mirror.omim.org/entry/601180