ribosomal RNA methyltransferase NOP2; nucleolar protein 2 homolog; nucleolar protein 1; proliferating-cell nucleolar antigen p120; proliferation-associated nucleolar protein p120 (NOP2, NOL1)

Function

• may play a role in the regulation of the cell cycle & the increased nucleolar activity that is associated with cell proliferation
• may act as ribosomal RNA methyltransferase
• interaction with MCRS1

Structure

• belongs to the methyltransferase superfamily, RsmB/NOP family

Compartment

nucleus, nucleolus

Alternative splicing

named isoforms=2

Expression

• expressed in G1 phase
• peaks during the early S phase of the cell cycle

More general terms

• methyltransferase
• nuclear protein
• phosphoprotein

Database

• UniProt: http://www.uniprot.org/uniprot/P46087.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=4839
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:4839
• OMIM: https://mirror.omim.org/entry/164031