neudesin (neuron-derived neurotrophic factor, secreted protein of unknown function, SPUF protein, NENF, SPUF)

Function

• displays neurotrophic activity & activates phosphorylation of MAPK1/ERK2, MAPK3/ERK1 & AKT1/AKT in primary cultured neurons
• does not have mitogenic activity in primary cultured astrocytes

Structure

belongs to the cytochrome b5 family, MAPR subfamily

Compartment

secreted

More general terms

• secreted protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q9UMX5.html