placenta-specific protein 1 (PLAC1)

Function

• role in placental development

Structure

• belongs to the PLAC1 family

Compartment

secreted

Expression

• expressed in placenta.
• localizes primarily to differentiated syncytiotrophoblast throughout gestation as well as to a small population of villous cytotrophoblasts
• also detected in maternal blood & rapidly disappears following delivery,
• not detected in other adult or fetal tissues
• up-regulated during trophoblast differentiation & by fibroblast growth factor 7 (FGF-7) in trophoblast cells

More general terms

• secreted protein
• placental protein

Database

• OMIM: https://mirror.omim.org/entry/300296
• UniProt: http://www.uniprot.org/uniprot/Q9HBJ0.html