retinoic acid receptor responder protein 2 (tazarotene-induced gene 2 protein, RAR-responsive protein TIG2, RARRES2,TIG2)

Compartment

secreted

Expression

• highly expressed in skin (basal & suprabasal layers of epidermis, hair follicles, endothelial cells)
• also found in pancreas, liver, spleen, prostate, ovary, small intestine, colon

Pathology

• inhibited in psoriatic lesions
• activated by tazarotene in epidermis of psoriatic lesions

More general terms

• secreted protein

Database

• OMIM: https://mirror.omim.org/entry/601973
• UniProt: http://www.uniprot.org/uniprot/Q99969.html