Fc receptor-like & mucin-like 1 (Fc receptor-like A, Fc receptor homolog expressed in B-cells, Fc receptor-related protein X, FcRX, Fc receptor-like protein, FCRLA, FCRL, FCRL1, FCRLM1, FCRX, FREB, UNQ291/PRO329)
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Function
- role in B-cell differentiation & lymphomagenesis (putative)
Structure
- monomer or homodimer, disulfide-linked
- contains 2 Ig-like C2-type domains (immunoglobulin-like)
Compartment
Alternative splicing
named isoforms=8
Expression
- expressed specifically in primary & secondary lymphoid tissues, including lymph node, spleen & tonsil
- specifically expressed in B-cells
- also expressed in melanoma & melanocytes