phospholipid transfer protein; lipid transfer protein II (PLTP)

Function

• converts HDL into larger & smaller particles
• may play a key role in extracellular phospholipid transport & modulation of HDL particles

Structure

• belongs to the BPI/LBP/plunc superfamily, BPI/LBP family

Compartment

secreted

Alternative splicing

named isoforms=2

Expression

• wide tissue distribution
• expressed in placenta > pancreas > lung > kidney > heart > liver > skeletal muscle > brain

More general terms

• lipid transfer protein
• secreted protein
• phosphoprotein

More specific terms

• non-specific phospholipid transfer protein
• phosphatidylcholine transfer protein; PC-TP; START domain-containing protein 2; StARD2; StAR-related lipid transfer protein 2 (PCTP, STARD2)
• phosphatidylcholine/phosphatidylinositol transfer protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=5360
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5360
• OMIM: https://mirror.omim.org/entry/172425
• UniProt: http://www.uniprot.org/uniprot/P55058.html