mediator of RNA polymerase II transcription subunit 16; mediator complex subunit 16; thyroid hormone receptor-associated protein 5; thyroid hormone receptor-associated protein complex 95 kD component; trap95; vitamin D3 receptor-interacting protein complex 92 kD component; DRIP92 (MED16, DRIP92, THRAP5)

Function

• transcriptional coactivation
• nuclear hormone receptor-mediated transactivation
• component of the mediator complex
• component of TRAP complex & ARC/DRIP complex

Compartment

nucleus

Alternative splicing

named isoforms=4

Notes

• uncertain whether Met-1 or Met-13 is the initiator

More general terms

• protein subunit

Component of

• thyroid hormone receptor associated protein complex (TRAP)
• activator-recruited cofactor (ARC)/DRIP

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=10025
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:10025
• OMIM: https://mirror.omim.org/entry/604062
• UniProt: http://www.uniprot.org/uniprot/Q9Y2X0.html