activating signal cointegrator 1 complex subunit 3; ASC-1 complex subunit p200; Helicase, ATP binding 1; trip4 complex subunit p200 (ASCC3 HELIC1)

Function

• enhances NF-kappa-B, SRF & AP1 transactivation
• part of activating-signal-cointegrator-1 complex (TRIP4 complex)

Structure

• belongs to the helicase family
• contains 2 helicase ATP-binding domains
• contains 2 helicase C-terminal domains
• contains 3 SEC63 domains

Compartment

cytoplasm

Expression

ubiquitous

More general terms

• protein subunit
• DEAD box ATP-dependent helicase
• phosphoprotein

Component of

• activating signal cointegrator 1 complex (ASC-1 complex, TRIP4 complex)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=10973
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:10973
• UniProt: http://www.uniprot.org/uniprot/Q8N3C0.html