DNA replication complex GINS protein SLD5 (GINS complex subunit 4, GINS4, SLD5)

Function

• component of the GINS complex
• GINS4 is important for GINS complex assembly
• forms a stable subcomplex with GINS1

Structure

belongs to the GINS4/SLD5 family

Compartment

cytoplasm (putative). nucleus

Alternative splicing

named isoforms=2

Pathology

significantly up-regulated in aggressive melanomas

More general terms

• protein subunit

Component of

• GINS complex

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:8429
• UniProt: http://www.uniprot.org/uniprot/Q9BRT9.html