GINS complex

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^[1]^[2]^[3]

Function

role in the initiation of DNA replication & progression of DNA replication forks
seems to bind preferentially to single-stranded DNA^[2]
interacts with DNA primase in vitro^[2]

Structure

consists of: PSF1/GINS1, PSF2/GINS2, PSF3/GINS3 SLD5/GINS4

Laboratory

Mass Spec: mass=98373; mass_error=13; electrospray^[3]

More general terms

References

↑ UniProt http://www.uniprot.org/uniprot/Q14691.html
↑ ^2.0 ^2.1 ^2.2 UniProt http://www.uniprot.org/uniprot/Q9BRX5.html
↑ ^3.0 ^3.1 Boskovic J et al Molecular architecture of the human GINS complex. EMBO Rep. 2007 Jul;8(7):678-84. Epub 2007 Jun 8. PMID: https://www.ncbi.nlm.nih.gov/pubmed/17557111

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