negative elongation factor C/D; NELF-C/D; TH1-like protein (NELFCD, TH1L, HSPC130)

Function

• essential component of the NELF complex
• interacts with ARAF1

Structure

belongs to the NELF-D family

Compartment

nucleus (probable)

Alternative splicing

• named isoforms=4

Alternative initiation

• alternative initiation at Met-10 of isoform NELF-C

Expression

• widely expressed
• expressed in heart, brain, lung, placenta, liver, skeletal muscle,cardiac muscle, adrenal, thyroid, kidney & pancreas

More general terms

• protein subunit

Component of

• negative elongation factor (NELF)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=51497
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:51497
• OMIM: https://mirror.omim.org/entry/605297
• UniProt: http://www.uniprot.org/uniprot/Q8IXH7.html