protein ZNF403; laryngeal carcinoma-related protein 1 (ZNF403, LCRG1, LZK1, GGNBP2)

Function

• may be involved in spermatogenesis interacts with GGN (putative)
• despite its name, does not contain a canonical C2H2-type zinc-finger & no zinc-finger is predicted by any prediction tool

Compartment

• cytoplasmic vesicle (putative)
• associated with vesicular structures (putative)

Alternative splicing

named isoforms=3

Expression

• expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney & pancreas
• expressed more abundantly in heart, pancreas & skeletal muscle

Pathology

• strongly down-regulated in 40% of primary laryngeal carcinoma & in 6 of 10 various cancer cell lines

More general terms

• other protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q9H3C7.html