protein Daple; Dvl-associating protein with a high frequency of leucine residues; hDaple; Hook-related protein 2 (HkRP2, KIAA1509, DAPL, CCDC88CE)

Function

• negative regulator of the canonical Wnt signaling pathway, acting downstream of DVL to inhibit CTNNB1/Beta-catenin stabilization (putative)
• interacts with the PDZ domain of DVL1 Stucture: homooligomer

Alternative splicing

named isoforms=3

More general terms

• other protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q9P219.html