cysteine-rich hydrophobic domain 2 protein (BrX-like translocated in leukemia, CHIC2, BTL)

Structure

• belongs to the CHIC family
• palmitoylated

Compartment

• cell membrane, cytoplasmic vesicle
• present at a Golgi-like vesicular compartment & at scattered vesicles

Pathology

• chromosomal translocation t(4;12)(q12;p13) involving CHIC2 with ETV6 is found in a form of acute myeloid leukemia (AML)

More general terms

• other protein

Database

• OMIM: https://mirror.omim.org/entry/604332
• UniProt: http://www.uniprot.org/uniprot/Q9UKJ5.html