complement-fixing antibody

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Introduction

An antibody that combines with antigen leading to the binding & activation of complement.

IgM strongly fixes complement (4+) by the classical pathway. IgG also fixes complement (1+) by the classical pathway.

Among the subtypes of IgG:

More general terms

More specific terms

Additional terms

References

  1. Clinical Diagnosis & Management by Laboratory Methods, 19th edition, J.B. Henry (ed), W.B. Saunders Co., Philadelphia, PA. 1996, pg 919