BMP-binding endothelial regulator protein (bone morphogenetic protein-binding endothelial cell precursor-derived regulator, protein crossveinless-2, hCV2, BMPER)

Function

• inhibitor of bone morphogenetic protein (BMP)
• regulates BMP responsiveness of osteoblasts & chondrocytes
• interacts with BMP4
• contains 1 TIL (trypsin inhibitory-like) domain
  • contains 5 VWFC domains
  • contains 1 VWFD domain

Compartment

secreted

Expression

expressed in lung, brain, primary chondrocytes

More general terms

• other protein

Additional terms

• bone morphogenetic protein (BMP)

Database

• OMIM: https://mirror.omim.org/entry/608699
• UniProt: http://www.uniprot.org/uniprot/Q8N8U9.html