glucokinase regulatory protein; glucokinase regulator (GCKR)

Function

• inhibits glucokinase by forming an inactive complex with the enzyme

Structure

• belongs to the GCKR family
• contains 2 SIS domains

Expression

• found in liver & pancreas
• not detected in muscle, brain, heart, thymus, intestine, uterus, adipose tissue, kidney, adrenal, lung or spleen

More general terms

• other protein

Additional terms

• glucokinase (GCK, hexokinase-D, hexokinase-4)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=2646
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2646
• OMIM: https://mirror.omim.org/entry/600842
• UniProt: http://www.uniprot.org/uniprot/Q14397.html