ubiquinone biosynthesis protein COQ4 homolog, mitochondrial; coenzyme Q biosynthesis protein 4 homolog (COQ4)

Function

• component of the coenzyme Q biosynthetic pathway
• role in organizing a multi-subunit CoQ enzyme complex required for coenzyme Q biosynthesis (putative)
• required for steady-state levels of other CoQ polypeptides
• cofactor biosynthesis; ubiquinone biosynthesis
• component of a multi-subunit CoQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 & COQ9 (putative)

Structure

belongs to the COQ4 family

Compartment

• isoform 1: mitochondrion inner membrane
• peripheral membrane protein; matrix side

Alternative splicing

named isoforms=2

Expression

• expressed ubiquitously
• high expression in liver, lung & pancreas

More general terms

• mitochondrial membrane protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=51117
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:51117
• OMIM: https://mirror.omim.org/entry/612898
• UniProt: http://www.uniprot.org/uniprot/Q9Y3A0.html