Nik-related protein kinase (NRK)

Function

• may phosphorylate cofilin-1 & induce actin polymerization during late stages of embryogenesis
• TNF-alpha-induced signaling pathway

Structure

• belongs to the protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily
• contains 1 CNH domain
• contains 1 protein kinase domain

Alternative splicing

named isoforms=3

More general terms

• serine/threonine kinase

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=203447
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:203447
• OMIM: https://mirror.omim.org/entry/300791
• UniProt: http://www.uniprot.org/uniprot/Q7Z2Y5.html