testis-specific serine/threonine protein kinase 6; TSK-6; TSSK-6; testis-specific kinase 6; cancer/testis antigen 72; CT72; serine/threonine protein kinase SSTK; small serine/threonine kinase (TSSK6, SSTK, FKSG82)

Function

• sperm production & function
• DNA condensation during postmeiotic chromatin remodeling
• interacts with the heatshock proteins HSPCB, HSPA8, HAPA1A; interactions appear to be required for TSSK6 kinase activity
• autophosphorylated

Cofactor: Mg+2

Structure

• belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family
• contains 1 protein kinase domain

Expression

• expressed in testis > colon, small intestine, ovary, prostate, thymus, spleen, peripheral blood leukocytes

More general terms

• serine/threonine kinase
• testis-specific protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=83983
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:83983
• OMIM: https://mirror.omim.org/entry/610712
• UniProt: http://www.uniprot.org/uniprot/Q9BXA6.html