dipeptidase 2 (DPEP2)

Function

• probable metalloprotease
• hydrolyzes leukotriene D4 (LTD4) into leukotriene E4 (LTE4) (putative)
• hydrolysis of dipeptides

Cofactor: Zn+2

Inhibition:

• inhibited by L-penicillamine

Structure

• homodimer, disulfide-linked
• belongs to the peptidase M19 family

Compartment

membrane, GPI-anchor

Alternative splicing

named isoforms=2

More general terms

• dipeptidase
• glypiated protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q9H4A9.html